Product Datasheet  
ATN1 Antibody  
Catalog Number: 34473  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P54259
    NCBI Gene ID: 1822
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from N-terminal of human ATN1.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • ATN1; Atrophin-1; Dentatorubral-pallidoluysian atrophy protein; DRPL;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ATN1 protein.
  • Applications：  
  • WB
  • Background：  
  • Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation By similarity. Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Asn (polyQ) repeats.

    Nagafuchi S., Nat. Genet. 8:177-182(1994).
    Onodera O., Am. J. Hum. Genet. 57:1050-1060(1995).
    Margolis R.L., Brain Res. Mol. Brain Res. 36:219-226(1996).



 
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