Serpin B5 Antibody

Catalog Number:

34298

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P36952
NCBI Gene ID: 5268

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human Serpin B5.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Serpin B5 protein.

Applications:

WB

Background:

Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Zou Z., Science 263:526-529(1994).
Pemberton P.A., J. Biol. Chem. 270:15832-15837(1995).
Law R.H., J. Biol. Chem. 280:22356-22364(2005).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF