Product Datasheet
Serpin B5 Antibody
Catalog Number: 34298
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P36952
NCBI Gene ID: 5268
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human Serpin B5.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Serpin B5 [Precursor]; Maspin; Protease inhibitor 5; SERPINB5; PI5
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total Serpin B5 protein.
- Background:
- Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Zou Z., Science 263:526-529(1994).
Pemberton P.A., J. Biol. Chem. 270:15832-15837(1995).
Law R.H., J. Biol. Chem. 280:22356-22364(2005).
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