FRS3 Antibody

Catalog Number:

34249

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O43559
NCBI Gene ID: 10817

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human FRS3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FRS3 protein.

Applications:

WB

Background:

Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.

Xu H., J. Biol. Chem. 273:17987-17990(1998).
Mungall A.J., Nature 425:805-811(2003).
The MGC Project Team; Genome Res. 14:2121-2127(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF