Product Datasheet  
FRS3 Antibody  
Catalog Number: 34249  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O43559
    NCBI Gene ID: 10817
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human FRS3.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • fibroblast growth factor receptor substrate 3; FRS2B; FRS2beta; MGC17167; SNT-2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total FRS3 protein.
  • Applications：  
  • WB
  • Background：  
  • Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.

    Xu H., J. Biol. Chem. 273:17987-17990(1998).
    Mungall A.J., Nature 425:805-811(2003).
    The MGC Project Team; Genome Res. 14:2121-2127(2004).



 
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