FGF23 Antibody

Catalog Number:

34248

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9GZV9
NCBI Gene ID: 8074

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human FGF23.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FGF23 protein.

Applications:

WB IF

Background:

Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL By similarity. Acts directly on the parathyroid to decrease PTH secretion By similarity. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

Yamashita T., Biochem. Biophys. Res. Commun. 277:494-498(2000).
White K.E., Nat. Genet. 26:345-348(2000).
Shimada T., Proc. Natl. Acad. Sci. U.S.A. 98:6500-6505(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF