Product Datasheet  
FGF23 Antibody  
Catalog Number: 34248  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9GZV9
    NCBI Gene ID: 8074
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human FGF23.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

    Immunofluorescence: 1:100~1:500
  • other_names：  
  • Fibroblast growth factor 23; FGF-23; Tumor-derived hypophosphatemia-inducing factor; HYPF;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total FGF23 protein.
  • Applications：  
  • WB IF
  • Background：  
  • Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL By similarity. Acts directly on the parathyroid to decrease PTH secretion By similarity. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

    Yamashita T., Biochem. Biophys. Res. Commun. 277:494-498(2000).
    White K.E., Nat. Genet. 26:345-348(2000).
    Shimada T., Proc. Natl. Acad. Sci. U.S.A. 98:6500-6505(2001).



 
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