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Cytochrome P450 2J2 Antibody

Catalog Number:

34239
other_names: Cytochrome P450 2J2; EC 1.14.14.1; CYPIIJ2; Arachidonic acid epoxygenase; CP2J2

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P51589
NCBI Gene ID: 1573

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from inetrnal of human Cytochrome P450 2J2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cytochrome P450 2J2 protein.

Applications:

WB IHC IF

Background:

This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.

Wu S., J. Biol. Chem. 271:3460-3468(1996).
King L.M., Mol. Pharmacol. 61:840-852(2002).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

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