Product Datasheet
Cytochrome P450 2J2 Antibody
Catalog Number: 34239
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P51589
NCBI Gene ID: 1573
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from inetrnal of human Cytochrome P450 2J2.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
- other_names:
- Cytochrome P450 2J2; EC 1.14.14.1; CYPIIJ2; Arachidonic acid epoxygenase; CP2J2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total Cytochrome P450 2J2 protein.
- Background:
- This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.
Wu S., J. Biol. Chem. 271:3460-3468(1996).
King L.M., Mol. Pharmacol. 61:840-852(2002).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
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