Cytochrome P450 2E1 Antibody

Catalog Number:

34238

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P05181
NCBI Gene ID: 1571

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human Cytochrome P450 2E1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cytochrome P450 2E1 protein.

Applications:

WB IHC IF

Background:

Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.

Song B.-J., J. Biol. Chem. 261:16689-16697(1986).
Umeno M., Biochemistry 27:9006-9013(1988).
Deloukas P., Nature 429:375-381(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF