Product Datasheet  
Cytochrome P450 2E1 Antibody  
Catalog Number: 34238  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot: P05181
    NCBI Gene ID: 1571
  • Form of Antibody:  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthesized peptide derived from C-terminal of human Cytochrome P450 2E1.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names:  
  • CP2E1; CYP2E; CYPIIE1; Cytochrome P450 2E1; P450-J
  • Purification:  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity:  
  • The antibody detects endogenous levels of total Cytochrome P450 2E1 protein.
  • Applications:  
  • WB IHC IF
  • Background:  
  • Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.

    Song B.-J., J. Biol. Chem. 261:16689-16697(1986).
    Umeno M., Biochemistry 27:9006-9013(1988).
    Deloukas P., Nature 429:375-381(2004).




 
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