Product Datasheet
Cytochrome P450 2E1 Antibody
Catalog Number: 34238
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P05181
NCBI Gene ID: 1571
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human Cytochrome P450 2E1.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
- other_names:
- CP2E1; CYP2E; CYPIIE1; Cytochrome P450 2E1; P450-J
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total Cytochrome P450 2E1 protein.
- Background:
- Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
Song B.-J., J. Biol. Chem. 261:16689-16697(1986).
Umeno M., Biochemistry 27:9006-9013(1988).
Deloukas P., Nature 429:375-381(2004).
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