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Cytochrome P450 2D6 Antibody

Catalog Number:

34237
other_names: Cytochrome P450 2D6; EC 1.14.14.1; CYPIID6; P450-DB1; Debrisoquine 4-hydroxylase

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P10635
NCBI Gene ID: 1565

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human Cytochrome P450 2D6.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cytochrome P450 2D6 protein.

Applications:

WB

Background:

Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.

Tyndale R., Pharmacogenetics 1:26-32(1991).
Yokota H., Pharmacogenetics 3:256-263(1993).
Evert B., Naunyn Schmiedebergs Arch. Pharmacol. 350:434-439(1994).

References:

appl_detail:

Western blotting: 1:500~1:3000

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