Product Datasheet  
Cytochrome P450 2D6 Antibody  
Catalog Number: 34237  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P10635
    NCBI Gene ID: 1565
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human Cytochrome P450 2D6.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Cytochrome P450 2D6; EC 1.14.14.1; CYPIID6; P450-DB1; Debrisoquine 4-hydroxylase
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Cytochrome P450 2D6 protein.
  • Applications：  
  • WB
  • Background：  
  • Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.

    Tyndale R., Pharmacogenetics 1:26-32(1991).
    Yokota H., Pharmacogenetics 3:256-263(1993).
    Evert B., Naunyn Schmiedebergs Arch. Pharmacol. 350:434-439(1994).



 
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