Cytochrome P450 27A1 Antibody

Catalog Number:

34231

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q02318
NCBI Gene ID: 1593

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human Cytochrome P450 27A1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cytochrome P450 27A1 protein.

Applications:

WB

Background:

Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.

Cali J.J., J. Biol. Chem. 266:7774-7778(1991).
Guo Y.-D., Proc. Natl. Acad. Sci. U.S.A. 90:8668-8672(1993).
Leitersdorf E., J. Clin. Invest. 91:2488-2496(1993).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF