Product Datasheet  
Cytochrome P450 27A1 Antibody  
Catalog Number: 34231  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q02318
    NCBI Gene ID: 1593
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human Cytochrome P450 27A1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • 25-hydroxylase; 5-beta-cholestane-3-alpha; 7-alpha; 12-alpha-triol 27-hydroxylase; CP27A
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Cytochrome P450 27A1 protein.
  • Applications：  
  • WB
  • Background：  
  • Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.

    Cali J.J., J. Biol. Chem. 266:7774-7778(1991).
    Guo Y.-D., Proc. Natl. Acad. Sci. U.S.A. 90:8668-8672(1993).
    Leitersdorf E., J. Clin. Invest. 91:2488-2496(1993).



 
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