Cytochrome P450 26A1 Antibody

Catalog Number:

34230

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O43174
NCBI Gene ID: 1592

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human Cytochrome P450 26A1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cytochrome P450 26A1 protein.

Applications:

WB

Background:

Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.

White J.A., J. Biol. Chem. 272:18538-18541(1997).
Sonneveld E., Cell Growth Differ. 9:629-637(1998).
ova-Griffin M.E., Biochem. Biophys. Res. Commun. 252:487-491(1998).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF