Product Datasheet  
Cytochrome P450 26A1 Antibody  
Catalog Number: 34230  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O43174
    NCBI Gene ID: 1592
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human Cytochrome P450 26A1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Cytochrome P450 26A1; EC 1.14.-.-; Retinoic acid-metabolizing cytochrome; P450 retinoic acid-inactivating 1; P450RAI
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Cytochrome P450 26A1 protein.
  • Applications：  
  • WB
  • Background：  
  • Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.

    White J.A., J. Biol. Chem. 272:18538-18541(1997).
    Sonneveld E., Cell Growth Differ. 9:629-637(1998).
    ova-Griffin M.E., Biochem. Biophys. Res. Commun. 252:487-491(1998).



 
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