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p50 CDC37 Antibody

Catalog Number:

34191
other_names: CC37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co-chaperone Cdc37; p50Cdc37;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q16543
NCBI Gene ID: 11140

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human p50 CDC37.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total p50 CDC37 protein.

Applications:

WB

Background:

Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.

Stepanova L., Genes Dev. 10:1491-1502(1996).
Dai K., J. Biol. Chem. 271:22030-22034(1996).
Lamphere L., Oncogene 14:1999-2004(1997).

References:

appl_detail:

Western blotting: 1:500~1:3000

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