Product Datasheet
p50 CDC37 Antibody
Catalog Number: 34191
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q16543
NCBI Gene ID: 11140
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human p50 CDC37.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CC37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co-chaperone Cdc37; p50Cdc37;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total p50 CDC37 protein.
- Background:
- Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
Stepanova L., Genes Dev. 10:1491-1502(1996).
Dai K., J. Biol. Chem. 271:22030-22034(1996).
Lamphere L., Oncogene 14:1999-2004(1997).
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