5-HT-3A Antibody

Catalog Number:

34152

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P46098
NCBI Gene ID: 3359

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human 5-HT-3A.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total 5-HT-3A protein.

Applications:

WB

Background:

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

Miyake A., Mol. Pharmacol. 48:407-416(1995).
Belelli D., Mol. Pharmacol. 48:1054-1062(1995).
Yamada K., Biol. Psychiatry 60:192-201(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF