Product Datasheet
5-HT-3A Antibody
Catalog Number: 34152
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P46098
NCBI Gene ID: 3359
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human 5-HT-3A.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- 5-HT-3; 5-HT3R; 5-hydroxytryptamine 3 receptor; 5HT3R; HTR3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total 5-HT-3A protein.
- Background:
- This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Miyake A., Mol. Pharmacol. 48:407-416(1995).
Belelli D., Mol. Pharmacol. 48:1054-1062(1995).
Yamada K., Biol. Psychiatry 60:192-201(2006).
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