5-HT-1F Antibody

Catalog Number:

34150

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P30939
NCBI Gene ID: 3355

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human 5-HT-1F.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total 5-HT-1F protein.

Applications:

WB

Background:

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Lovenberg T.W., Proc. Natl. Acad. Sci. U.S.A. 90:2184-2188(1993).
Adham N., Proc. Natl. Acad. Sci. U.S.A. 90:408-412(1993).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF