Product Datasheet
5-HT-1F Antibody
Catalog Number: 34150
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P30939
NCBI Gene ID: 3355
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human 5-HT-1F.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- 5-hydroxytryptamine receptor 1F; 5-HT-1F; Serotonin receptor 1F; HTR1F; HTR1EL
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total 5-HT-1F protein.
- Background:
- G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Lovenberg T.W., Proc. Natl. Acad. Sci. U.S.A. 90:2184-2188(1993).
Adham N., Proc. Natl. Acad. Sci. U.S.A. 90:408-412(1993).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
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