14-3-3 η Antibody

Catalog Number:

34146

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q04917
NCBI Gene ID: 7533

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human 14-3-3 η.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total 14-3-3 η protein.

Applications:

WB IF

Background:

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

Swanson K.D., Biochim. Biophys. Acta 1216:145-148(1993).
Ichimura-Ohshima Y., J. Neurosci. Res. 31:600-605(1992).
Muratake T., Mol. Neurobiol. 11:223-230(1995).

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF