Product Datasheet  
14-3-3 η Antibody  
Catalog Number: 34146  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q04917
    NCBI Gene ID: 7533
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human 14-3-3 η.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

    Immunofluorescence: 1:100~1:500
  • other_names：  
  • 14-3-3 protein eta; Protein AS1; YWHAH; YWHA1;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total 14-3-3 η protein.
  • Applications：  
  • WB IF
  • Background：  
  • Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

    Swanson K.D., Biochim. Biophys. Acta 1216:145-148(1993).
    Ichimura-Ohshima Y., J. Neurosci. Res. 31:600-605(1992).
    Muratake T., Mol. Neurobiol. 11:223-230(1995).



 
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