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DYR1B Antibody

Catalog Number:

34135
other_names: DYR1B; Dual-specificity tyrosine-phosphorylation regulated kinase 1B; EC 2.7.12.1; MIRK; Mirk protein kinase

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9Y463
NCBI Gene ID: 9149

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DYR1B.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DYR1B protein.

Applications:

WB

Background:

Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.

Lee K., Cancer Res. 60:3631-3637(2000).
Grimwood J., Nature 428:529-535(2004).
Lim S., . Biol. Chem. 277:25040-25046(2002).

References:

appl_detail:

Western blotting: 1:500~1:3000

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