Product Datasheet
DYR1B Antibody
Catalog Number: 34135
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9Y463
NCBI Gene ID: 9149
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human DYR1B.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- DYR1B; Dual-specificity tyrosine-phosphorylation regulated kinase 1B; EC 2.7.12.1; MIRK; Mirk protein kinase
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total DYR1B protein.
- Background:
- Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.
Lee K., Cancer Res. 60:3631-3637(2000).
Grimwood J., Nature 428:529-535(2004).
Lim S., . Biol. Chem. 277:25040-25046(2002).
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