YBOX2 Antibody

Catalog Number:

34130

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9Y2T7
NCBI Gene ID: 51087

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human YBOX2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total YBOX2 protein.

Applications:

WB

Background:

Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay By similarity.

Tekur S., J. Androl. 20:135-144(1999).
The MGC Project Team; Genome Res. 14:2121-2127(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF