Product Datasheet
YBOX2 Antibody
Catalog Number: 34130
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9Y2T7
NCBI Gene ID: 51087
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human YBOX2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Y-box-binding protein 2; Germ cell-specific Y-box-binding protein; Contrin; MSY2 homolog; YBX2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total YBOX2 protein.
- Background:
- Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay By similarity.
Tekur S., J. Androl. 20:135-144(1999).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
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