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IKZF3 Antibody

Catalog Number:

34112
other_names: AIOL; IKZF3; ZNFN1A3; zinc finger protein Aiolos;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UKT9
NCBI Gene ID: 22806

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human IKZF3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total IKZF3 protein.

Applications:

WB

Background:

Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.

Hosokawa Y., Genomics 61:326-329(1999).
Liippo J.P., Eur. J. Immunol. 31:3469-3474(2001).
Perdomo J., J. Biol. Chem. 275:38347-38354(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000

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