Product Datasheet
IKZF3 Antibody
Catalog Number: 34112
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9UKT9
NCBI Gene ID: 22806
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human IKZF3.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- AIOL; IKZF3; ZNFN1A3; zinc finger protein Aiolos;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total IKZF3 protein.
- Background:
- Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.
Hosokawa Y., Genomics 61:326-329(1999).
Liippo J.P., Eur. J. Immunol. 31:3469-3474(2001).
Perdomo J., J. Biol. Chem. 275:38347-38354(2000).
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