FOXD3 Antibody

Catalog Number:

34110

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UJU5
NCBI Gene ID: 27022

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human FOXD3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FOXD3 protein.

Applications:

WB IHC

Background:

Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.

Gregory S.G., Nature 441:315-321(2006).
Guo Y., Proc. Natl. Acad. Sci. U.S.A. 99:3663-3667(2002).
Ramsey H.C., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF