Product Datasheet  
FOXD3 Antibody  
Catalog Number: 34110  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9UJU5
    NCBI Gene ID: 27022
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human FOXD3.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Forkhead box protein D3; HNF3/FH transcription factor genesis; FOXD3;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total FOXD3 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.

    Gregory S.G., Nature 441:315-321(2006).
    Guo Y., Proc. Natl. Acad. Sci. U.S.A. 99:3663-3667(2002).
    Ramsey H.C., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.



 
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