STAG3 Antibody

Catalog Number:

34109

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UJ98
NCBI Gene ID: 10734

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human STAG3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total STAG3 protein.

Applications:

WB

Background:

Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I By similarity.

Pezzi N., FASEB J. 14:581-592(2000).
The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Prieto I., EMBO Rep. 3:543-550(2002).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF