Product Datasheet
STAG3 Antibody
Catalog Number: 34109
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9UJ98
NCBI Gene ID: 10734
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human STAG3.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Cohesin subunit SA-3; Stromal antigen 3; Stromalin 3; SCC3 homolog 3; STAG3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total STAG3 protein.
- Background:
- Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I By similarity.
Pezzi N., FASEB J. 14:581-592(2000).
The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Prieto I., EMBO Rep. 3:543-550(2002).
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