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TRPS1 Antibody

Catalog Number:

34103
other_names: Zinc finger transcription factor Trps1; Zinc finger protein GC79; Tricho-rhino-phalangeal syndrome type I protein; TRPS1;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UHF7
NCBI Gene ID: 7227

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human TRPS1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TRPS1 protein.

Applications:

IHC

Background:

Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.

Momeni P., Nat. Genet. 24:71-74(2000).
Chang G.T.G., J. Natl. Cancer Inst. 92:1414-1421(2000).
Olsen J.V., Cell 127:635-648(2006).

References:

appl_detail:


Immunohistochemistry: 1:50~1:100

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