Product Datasheet
TRPS1 Antibody
Catalog Number: 34103
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9UHF7
NCBI Gene ID: 7227
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from N-terminal of human TRPS1.
- appl_detail:
Immunohistochemistry: 1:50~1:100
- other_names:
- Zinc finger transcription factor Trps1; Zinc finger protein GC79; Tricho-rhino-phalangeal syndrome type I protein; TRPS1;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total TRPS1 protein.
- Background:
- Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.
Momeni P., Nat. Genet. 24:71-74(2000).
Chang G.T.G., J. Natl. Cancer Inst. 92:1414-1421(2000).
Olsen J.V., Cell 127:635-648(2006).
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