DNA Polymerase λ Antibody

Catalog Number:

34098

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UGP5
NCBI Gene ID: 27343

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DNA Polymerase λ.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DNA Polymerase λ protein.

Applications:

WB

Background:

Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.

Aoufouchi S., Nucleic Acids Res. 28:3684-3693(2000).
Nagasawa K.I., J. Biol. Chem. 275:31233-31238(2000).
Ota T., Nat. Genet. 36:40-45(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF