Product Datasheet  
DNA Polymerase λ Antibody  
Catalog Number: 34098  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9UGP5
    NCBI Gene ID: 27343
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human DNA Polymerase λ.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:500~1:3000

  • other_names：  
  • DNA polymerase lambda; EC 2.7.7.7; EC 4.2.99.-; Pol Lambda; DNA polymerase kappa
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total DNA Polymerase λ protein.
  • Applications：  
  • WB
  • Background：  

  • Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.

    Aoufouchi S., Nucleic Acids Res. 28:3684-3693(2000).
    Nagasawa K.I., J. Biol. Chem. 275:31233-31238(2000).
    Ota T., Nat. Genet. 36:40-45(2004).




 
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