HEY2 Antibody

Catalog Number:

34094

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UBP5
NCBI Gene ID: 23493

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human HEY2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HEY2 protein.

Applications:

WB

Background:

Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

Chin M.T., J. Biol. Chem. 275:6381-6387(2000).
Nakagawa O., Proc. Natl. Acad. Sci. U.S.A. 97:13655-13660(2000).
Iso T., Mol. Cell. Biol. 21:6071-6079(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF