Product Datasheet
HEY2 Antibody
Catalog Number: 34094
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9UBP5
NCBI Gene ID: 23493
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human HEY2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Hairy/enhancer-of-split related with YRPW motif protein 2; Cardiovascular helix-loop-helix factor 1; hCHF1; Hairy and enhancer of split-related protein 2; HESR-2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total HEY2 protein.
- Background:
- Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Chin M.T., J. Biol. Chem. 275:6381-6387(2000).
Nakagawa O., Proc. Natl. Acad. Sci. U.S.A. 97:13655-13660(2000).
Iso T., Mol. Cell. Biol. 21:6071-6079(2001).
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