Product Datasheet  
HEY2 Antibody  
Catalog Number: 34094  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot: Q9UBP5
    NCBI Gene ID: 23493
  • Form of Antibody:  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthesized peptide derived from internal of human HEY2.
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Western blotting: 1:500~1:3000

  • other_names:  
  • Hairy/enhancer-of-split related with YRPW motif protein 2; Cardiovascular helix-loop-helix factor 1; hCHF1; Hairy and enhancer of split-related protein 2; HESR-2
  • Purification:  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity:  
  • The antibody detects endogenous levels of total HEY2 protein.
  • Applications:  
  • WB
  • Background:  
  • Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

    Chin M.T., J. Biol. Chem. 275:6381-6387(2000).
    Nakagawa O., Proc. Natl. Acad. Sci. U.S.A. 97:13655-13660(2000).
    Iso T., Mol. Cell. Biol. 21:6071-6079(2001).



 
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