DCP1A Antibody

Catalog Number:

34074

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9NPI6
NCBI Gene ID: 55802

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DCP1A.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DCP1A protein.

Applications:

WB

Background:

Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.

Lykke-Andersen J., Mol. Cell. Biol. 22:8114-8121(2002).
Bai R.-Y., Nat. Cell Biol. 4:181-190(2002).
Ota T., Nat. Genet. 36:40-45(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF