Product Datasheet  
DCP1A Antibody  
Catalog Number: 34074  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9NPI6
    NCBI Gene ID: 55802
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human DCP1A.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • mRNA-decapping enzyme 1A; EC 3.-.-.-; Transcription factor SMIF; Smad4-interacting transcriptional co-activator; DCP1A
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total DCP1A protein.
  • Applications：  
  • WB
  • Background：  
  • Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.

    Lykke-Andersen J., Mol. Cell. Biol. 22:8114-8121(2002).
    Bai R.-Y., Nat. Cell Biol. 4:181-190(2002).
    Ota T., Nat. Genet. 36:40-45(2004).



 
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