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RHBT2 Antibody

Catalog Number:

34052
other_names: Rho-related BTB domain-containing protein 2; Deleted in breast cancer 2 gene protein;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9BYZ6
NCBI Gene ID: 23221/9886

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human RHBT2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RHBT2 protein.

Applications:

WB

Background:

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.

Ramos S., Gene 298:147-157(2002).
Nagase T., DNA Res. 5:277-286(1998).
Nakajima D., DNA Res. 9:99-106(2002).

References:

appl_detail:

Western blotting: 1:500~1:3000

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