Product Datasheet
RHBT2 Antibody
Catalog Number: 34052
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9BYZ6
NCBI Gene ID: 23221/9886
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human RHBT2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Rho-related BTB domain-containing protein 2; Deleted in breast cancer 2 gene protein;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total RHBT2 protein.
- Background:
- The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.
Ramos S., Gene 298:147-157(2002).
Nagase T., DNA Res. 5:277-286(1998).
Nakajima D., DNA Res. 9:99-106(2002).
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