DUSP16 Antibody

Catalog Number:

34049

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9BYG9
NCBI Gene ID: 80824

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DUSP16.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DUSP16 protein.

Applications:

WB IF

Background:

This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.

Masuda K., J. Biol. Chem. 276:39002-39011(2001).
Hoornaert I., Oncogene 22:7728-7736(2003).
Nagase T., DNA Res. 7:347-355(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF