Product Datasheet
DUSP16 Antibody
Catalog Number: 34049
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9BYG9
NCBI Gene ID: 80824
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human DUSP16.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
- other_names:
- Dual specificity protein phosphatase 16; EC 3.1.3.48; EC 3.1.3.16; Mitogen-activated protein kinase phosphatase 7; MAP kinase phosphatase 7
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total DUSP16 protein.
- Background:
- This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.
Masuda K., J. Biol. Chem. 276:39002-39011(2001).
Hoornaert I., Oncogene 22:7728-7736(2003).
Nagase T., DNA Res. 7:347-355(2000).
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