ATF6B Antibody

Catalog Number:

34039

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q99941
NCBI Gene ID: 1388

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ATF6B.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATF6B protein.

Applications:

WB

Background:

Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN9CCAC[GA]-3') when NF-Y is bound to ERSE.

Min J., Genomics 30:149-156(1995).
Khanna A., Biochem. J. 319:81-89(1996).
Xie T., Genome Res. 13:2621-2636(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF