Product Datasheet
ATF6B Antibody
Catalog Number: 34039
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q99941
NCBI Gene ID: 1388
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human ATF6B.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Cyclic AMP-dependent transcription factor ATF-6 beta; Activating transcription factor 6 beta; ATF6-beta; cAMP-responsive element-binding protein-like 1; cAMP response element-binding protein-related protein
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ATF6B protein.
- Background:
- Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN9CCAC[GA]-3') when NF-Y is bound to ERSE.
Min J., Genomics 30:149-156(1995).
Khanna A., Biochem. J. 319:81-89(1996).
Xie T., Genome Res. 13:2621-2636(2003).
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