MKL1 Antibody

Catalog Number:

34018

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q969V6
NCBI Gene ID: 57591

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human MKL1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MKL1 protein.

Applications:

WB

Background:

Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation By similarity.

Ma Z., Nat. Genet. 28:220-221(2001).
Mercher T., Proc. Natl. Acad. Sci. U.S.A. 98:5776-5779(2001).
Nagase T., DNA Res. 7:65-73(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF